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Author Topic: So HRT IS SAFE after all  (Read 42234 times)

skkb

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So HRT IS SAFE after all
« on: October 20, 2015, 03:52:28 PM »

All over the papers yesterday that after new "research " the dangers of HRT have been overplayed and HRT is safe for women to take long term, for life if they want, alleluia, wish they'd said that 12 months ago and I hadn't suffered for best part of a year after coming off it, particularly as I felt GREAT when on it. Should I return to my lovely HRT or will more "research " prove this research to be flawed as well later on ......grrrrr
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CLKD

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Re: So HRT IS SAFE after all
« Reply #1 on: October 20, 2015, 04:06:01 PM »

Return to your GP!  Also have a read of the other threads here about yesterday's Press release  ;)
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CLKD

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Re: So HRT IS SAFE after all
« Reply #2 on: October 20, 2015, 04:21:56 PM »

Is it advanced publicity?  It's different to what is expected from NICE in November  ;)
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CLKD

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Re: So HRT IS SAFE after all
« Reply #3 on: October 20, 2015, 04:26:30 PM »

That's how I read it.  Don't care, won't care - GPs need to justify themselves more clearly now if they don't want to spend the budget on HRT  ;)
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Mary G

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Re: So HRT IS SAFE after all
« Reply #4 on: October 20, 2015, 06:42:06 PM »

CLKD, agreed.  Nothing is 100% safe, how safe is contraceptive pill or any other medication?  One thing is for sure, the risk is pretty minimal for most people unless they have a family history of various illnesses and there is no evidence to suggest that the vast majority of women cannot benefit from this life changing medication. 

If you have decided not to take HRT and are happy with that decision then you don't have a problem but if you want/need it then you should be free to take it. 
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CLKD

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Re: So HRT IS SAFE after all
« Reply #5 on: October 20, 2015, 06:44:42 PM »

Yep.  Informed choices? but GPs have to begin supporting ladies and be more transparent about why they prefer not to prescribe HRT! including Surgery budgets  ;)
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honeybun

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Re: So HRT IS SAFE after all
« Reply #6 on: October 20, 2015, 06:46:14 PM »

The study they are reporting on involved 80 women.
A bit of a farce to be honest......we have more women on here.

We really need to see what the NICE report says and then we maybe have something to beat our doctors over the head with. They can't ignore that.

But until then.....personally I think it's been a quiet news day.  ::)


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CLKD

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Re: So HRT IS SAFE after all
« Reply #7 on: October 20, 2015, 06:50:10 PM »

We need Drugs Companies to be honest too !  They need to put the whole Report out there, not cherry pick to show the Press etc. the bits that push for their drug to be accepted onto the Trials and leave out those iffy areas which didn't work!
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Hurdity

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Re: So HRT IS SAFE after all
« Reply #8 on: October 20, 2015, 07:22:05 PM »

We just need clarify!

1  World Menopause Day was Sunday 19th October
2  The NICE Guidelines come out soon - mid November. The full report cites the latest research but the summary report  (which most people will read) provides prescribing and management guidelnines for medical practitioners.
3  Yesterday the papers reported on some new research which happened to be published.

Three different things. Emma reported on all of these on the thread entitled "World Menopause Day and NICE" here:
http://www.menopausematters.co.uk/forum/index.php/topic,29497.0.html

There was some discussion.

Several other member reported on the news as they reported is on threads here:
http://www.menopausematters.co.uk/forum/index.php/topic,29505.0.html

and here:
http://www.menopausematters.co.uk/forum/index.php/topic,29498.0.html


 :bang: :bang: :bang: :bang: (first time I think I've used that icon)
I really don't know why some members - Prajna, Grangravy and honeybun are knocking the study or trying to finding fault with it - or are suspicious of it.

I think everyone is agreed that news articles (especially in certain newspapers) are often sensational, misleading, and focus on headline grabbing sometimes at the expense of the accuracy of what is being reported. No-one disputes that.

We also all agree we would like to see the research summary. We don't know if the authors of the study are claiming that HRT is safe (ie using those words or similar) in their press release of the results of their study.

I would suggest that no scientist would ever make those conclusions on a subject so significant as this, on the basis of one study. As I said yesterday - reporting what was said on this site and by Dr Currie, it adds to the recent body of evidence which comes to the same conclusion - as does the British Menopause Society http://www.thebms.org.uk/newsitem.php?newsid=87  which also recognises the small sample size etc etc

How can a study involving 136 women ( of whom 80 took HRT) be a farce? From what little we know a large group of women (80) were scanned every year for 10 years. At its best and if resources were available,  other physiological and structural information will have been measured and recorded over the years, probably yielding an enormous amount of useful information about detailed changes that take place in a woman's body whilas she ages while taking HRT. The safety conclusion may well be one of many - but the most headline grabbing.  The scans alone surely will yield incredibly useful data and will hopefully provided new medical insights.

How can this (what I imagine to be a detailed study) be a "bit of a farce", "suspicious" and a "limp sparkler"?? I am pleased that all of these studies are being carried out and reported so that we can find the original and read about them. It's very unfortunate that the press are sensationalist - but then they always have been.

Science (and through science, medicine) progresses through the accumulation of evidence produced in studies that test theories/hypotheses. Results are either consistent with or refute the hypotheses which then might have to be changed as a result.

The Women's Health Initiative and Million Women Study - initially did just that - and came to the conclusion that HRT was inherently unsafe - notably in older women and with long term use. These studies were later found to be flawed and the data re-evaluated and the conclusions (even from these flawed studies), modified. Later studies with better experimental design have come to different conclusions and the body of evidence is now accumulating which means these ideas need to be changed.

Most importantly many recent studies and trials are more rigorous, and specifiy for example which type of HRT is used. I hope the result of this new study does likewise - because different results have been obtained from different HRT types.

Also it is all about risk - especially absolute risk (eg 1 in 100), rather than relative risk (twice as risky - which would eg be 2 in a 100), which needs to be looked at compared to other risky things we do medication, alcohol, smoking, being fat, not exercising etc

The NICE Guidelines will also be reported widely and hopefully with much trumpeting!

Hurdity x




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CLKD

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Re: So HRT IS SAFE after all
« Reply #9 on: October 20, 2015, 07:34:46 PM »

 ;) ………. quality of Life is still my mantra ……… regardless.
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honeybun

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Re: So HRT IS SAFE after all
« Reply #10 on: October 20, 2015, 07:39:59 PM »

I'm not knocking it but it was not much of a survey as it only included 80 women.

The NICE report will be inclusive and our GPs will hopefully take heed but to expect them to take notice of such a small survey.....well I don't think so.
As we all know, you can bend the results every which way if you want.


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CLKD

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Re: So HRT IS SAFE after all
« Reply #11 on: October 20, 2015, 07:41:46 PM »

GPs rarely get time to read 'current' reports  ::)  :-\ ……. hopefully the NICE Report will be 'inclusive' - of what though?  Will it recommend HRT/not?  Is it The Bible for medics.?
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Hurdity

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Re: So HRT IS SAFE after all
« Reply #12 on: October 20, 2015, 07:55:13 PM »

Re NICE the draft report (full report) and summary have been available for some time. What's being published in mid November is the full report and separate summary ( prescribing guidelines etc) after the consultation process.

There is plenty of information about it here which has been available since June and linked to on here. The full report gives published sources to justify every recommendation they make - but probably too late for the latest study. It is unlikely that the final recommendations will differ greatly from the draft.

Here is the draft  guideline ( summary)
https://www.nice.org.uk/guidance/GID-CGWAVE0639/documents/menopause-draft-guideline-nice2

Here is the detailed report:
https://www.nice.org.uk/guidance/GID-CGWAVE0639/documents/menopause-full-guideline2

Here are all the documents listed:
https://www.nice.org.uk/guidance/indevelopment/gid-cgwave0639/documents

Here is the process and timeline:
https://www.nice.org.uk/guidance/indevelopment/gid-CGWAVE0639?

All reputable published scientific studies are peer reviewed before publication in reputable journals so results and data should be transparent. I agree that interpretation can be misleading even if correct eg in an experiment to test the effectiveness of something (X) you might find 80/100 showed it was effective and 20/100 ineffective. This could be reported either way by the press to give a headline either way X was effective or 1/5 found X to be ineffective.

Yes  I agree CLKD....  quality of life!!!!!!  :)

BTW this explains what NICE does and the role of guidelines:
https://www.nice.org.uk/about/what-we-do

Hurdity x


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Mary G

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Re: So HRT IS SAFE after all
« Reply #13 on: October 20, 2015, 08:51:05 PM »

Good post Hurdity.  I would add that HRT seems to come in for far heavier criticism than other medications and people seem to want greater guarantees and certainties for HRT than they do for other drugs.  People in general seem to happily leap on the downside of HRT while overlooking the downside of other medication.  Having read all the newspaper links, I noticed lots of negative comments on the Telegraph article with people being suspicious of Big Pharma and generally very cynical about HRT.  Are they that cynical about all studies and medications?  For some reason, the whole subject seems to be very emotive.

This may sound rather unconventional but I think that there is a fault in the female make up and it would be better if we lost just enough hormones to stop us being reproductive but enough to keep all the vital organs healthy and not have the terrible symptoms that come (for some) with the menopause.  Men produce sex hormones all their lives and it would be better if we produced slightly more all our lives.  HRT is the only way to combat this fault. 
« Last Edit: October 20, 2015, 11:57:04 PM by Mary G »
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Dana

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Re: So HRT IS SAFE after all
« Reply #14 on: October 21, 2015, 01:38:22 AM »

Good post Hurdity.  I would add that HRT seems to come in for far heavier criticism than other medications and people seem to want greater guarantees and certainties for HRT than they do for other drugs.  People in general seem to happily leap on the downside of HRT while overlooking the downside of other medication.  Having read all the newspaper links, I noticed lots of negative comments on the Telegraph article with people being suspicious of Big Pharma and generally very cynical about HRT.  Are they that cynical about all studies and medications?  For some reason, the whole subject seems to be very emotive.


This may play into my feminist "conspiracy theory" psyche, but I think HRT gets so much negative attention sometimes because how dare women have a medication that makes them feel good. It's fine for men to have Viagra. Men are entitled to continue to perform long past their use by dates. That's their right, but women should be reminded every single day of their post-meno lives that they are no long useful, attractive or vital.

Sadly even women can be our own worst enemies sometimes because they feel they need to be put upon stoic martyrs who should "suffer in silence" - or even worse they think that women who complain about menopause are exaggerating. Society, and especially the media, knows full-well that it takes very little to make women feel guilty or scared about something, and we play right into their hands sometimes.

You didn't breastfeed your baby? - feel guilty.
You had some "me-time" instead of being at the beck and call of your family - feel guilty.
You didn't clean the house this week - feel guilty.
You took HRT and felt better - feel guilty.
« Last Edit: October 21, 2015, 01:40:07 AM by Dana »
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