Hi, thanks Taz, for posting that link. I have just read it as that is of great interest to me due to suffering severe perimenopausal pms which is making my life (& the rest of the househo!d's lives) a misery. What LeeJane has mentioned is a good point, though, because what happens when you stop taking the AD's for the 'good' time during the cycle? Do you get withdrawal symptoms? Also, when I first go on AD's, I get INCREASED anxiety for the first week. I wou!d definitely take them if I didn't get the horrib!e side effects - I seem to have become very sensitive to a lot of meds recently. Has anyone out there tried this method & had success with it? X