I have been on Vagifem for 4 years now. Since the change to the 10 mcg I need to do a reload about every 9 - 10 months which sorts it out then back to my 3 times a week.
Hurdity it seems so much harder after a hysyerectomy as I didn't know where I was in menopause until the hot flushes started as there were no other signs without the bleeding. My levels seemed to keep dropping for about 3 years and then the flushes got milder and less often. Nowadays I can go several days without one but then they seem to jump out at me when I don't expect it just to remind me that they have not finished with me yet.
However from reading around this site I realise that I have been one of the lucky ones and not suffered too much for too long. Some of the ladies, well I don't know how they keep going with what they have to put up with.