My new doctor, a family practitioner MD and a Phd said all her female patients will be on the 0.050 patch cut in half to equal 0.25 until the day they die. Three gynaes have said the same thing to me.
I would never take oral again as it goes through the liver and there is where clots are thought by many to begin. My mother is now 97 and still on Premarin, ugh. She did get carcinoma in situ at 84 and the oncologist said she could go right back on Premarin. She still drives. Everyone is different for sure. I have varicose veins, always have had and surgery for them, but still use patch and always will.