Hi monalisa, sorry to hear that, really distressing. I don't think HRT alone can be blamed for the migraine attack. I think most of your symptoms, joint aches, bladder prolapse and now migraine could be due to HRT withdrawal, particularly the progestin part of Evorel Conti, norethisterone. Fluoxetine won't touch the prolapse and joint aches, I'm afraid. I understand you're on the lowest dose of Sandrena gel? Maybe your body had better absorption from the patch and now you might be having fluctuations on the gel? That could explain the migraine. Just some thoughts you can discuss with your GP or Gynae.