Menopause Matters Forum

Menopause Discussion => All things menopause => Topic started by: Nik2502 on November 02, 2018, 10:26:42 AM

Title: Evorel 75 - need more?
Post by: Nik2502 on November 02, 2018, 10:26:42 AM
Hi
I've been on Evorel 75 since August and had felt amazing - until this week. I'm suddenly back to feeling depressed and anxiety and struggling to cope.
Do any of you lady's have this experience? Is it normal to occasionally feel like this (as oppose to all the time before)?
I'm a large lady and have had such a battle to get HRT in the first place - one consultant refused to even prescribe. I know hormones or lack of them are a major part of my mental health problems which started with the menopause.
I'm 48 and started menopause at 36.
Any advice would be much appreciated x
Title: Re: Evorel 75 - need more?
Post by: Dancinggirl on November 02, 2018, 10:42:10 AM
I think fluctuations in mood are very normal whether on hrt or not - perhaps you are vitamin D deficient. Symptoms of Vit D deficiency are low energy, low mood, aching joints and low immunity.
Exercise is great for general health and particularly lifting the mood - could you get out for 10 minute brisk walks 3 times a day and/or go to a dance class?
If you struggle with your weight it would be wise to try and get your BMI down now, as it gets harder as one gets older and if you need to stay on HRT then you need to control weight or they might well take the HRT away due to risks. DG x
Title: Re: Evorel 75 - need more?
Post by: SueLW on November 02, 2018, 10:59:17 AM
Transdermal patches or gel is the ideal HRT for anyone with weight issues (me!).  Very much less risk.  Your GP was wrong to refuse to prescribe for someone who went into menopause early.

Stick with what you are doing for a week and see if things improve.  It might just be a bit of a down week.  We will get those.  If things improve you will know that was what it was.  If they don't then you could experiment.  The first thing we all think is "I need more" but I personally have found that I often need less in those cases.  You have been using the 75 patch for a while so your levels have risen somewhat and now your body may be struggling to deal with it.  The easiest way to experiment is to remove your patch and see how you feel for a 24 or 36hr period.  When I used patched I found I needed to do this quite regularly to adjust the dose I suppose.  Once you start to feel worse you know you need to put the patch back on. 

If, on the other hand, removing the patch starts to make you feel worse you know you need a bit more and might need to ask for 100 patch.  We all absorb differently.  It's not the size of the patch that's important.  It's what your oestrogen levels are like inside your body.
Title: Re: Evorel 75 - need more?
Post by: Nik2502 on November 02, 2018, 11:20:24 AM
Thank you ladies. I'll give myself a few more days to see how I am.
I just hate waking up every day not knowing how I'm going to feel. I've had three very stable months and have probably lulled myself into a false sense of security. I just hoped I'd never feel like this again!
Title: Re: Evorel 75 - need more?
Post by: Robin on November 05, 2018, 06:42:35 AM
Hi Nik,
You mentioned that your dips are cyclical so I wondered if you've considered whether the progestogen you're using might be causing them?
Title: Re: Evorel 75 - need more?
Post by: Noheroicsplease on November 05, 2018, 08:57:13 AM
Hi,

I've been on Estradot 75 for about 6 weeks. I change it every 3 days, on advice of meno consultant - I was taking 4 pumps of Estrogel daily and absorbing nothing, estrogen was at an all time low - off the scale low - but recent blood tests show that I'm nearing 200 levels of estrogen.

I feel better, for sure. BUT, i've also had dips. I've wondered if I'm getting enough progesterone via the mirena.

The dips pass. I also take testosterone, 2 pumps of Tostran a week.

x
Title: Re: Evorel 75 - need more?
Post by: Nik2502 on November 05, 2018, 10:01:04 AM
Hi Nik,
You mentioned that your dips are cyclical so I wondered if you've considered whether the progestogen you're using might be causing them?

Hi Robin
No it doesn't seem to be. I'm finding the vaginal utrogestan great compared to oral.
I've felt so good since the summer and stupidly thought I'd found the miracle ‘cure' but clearly not.
Nic x
Title: Re: Evorel 75 - need more?
Post by: Robin on November 05, 2018, 10:48:04 AM
It's so frustrating when you think you've found the solution but maybe it's just a spell of your own hormonal fluctuations going on in the background rather than being caused by the HRT. I'm much better than I was now that I have HRT but I can still feel my own hormones fluctuating in the background causing mood dips they're not nearly as severe they were although my starting point was as bad as it could get. To to be where I am now although a long way from my 'normal ' it feels like a miraculous improvement. I used 75 for a while then moved up to 100. Have you tried testosterone? I was quite reticent but it has helped my mood enormously and definitely worth trying. Hope you feel better soon
Robin x
Title: Re: Evorel 75 - need more?
Post by: Nik2502 on November 05, 2018, 11:45:38 AM
Thanks Robin. I've actually booked to see Dr Julie Ayres in Leeds on Thursday. I've heard mixed reviews about her and testosterone but will see what she says. I just want my life back! I've had to take yet another week off work to pull myself around and I can't keep doing it.

I've also done research and found antibiotics can disrupt your absorption of HRT and I was started on them last week for a skin problem. I've stopped them as I can cope better with my skin than the anxiety and low mood!
Title: Re: Evorel 75 - need more?
Post by: Hurdity on November 05, 2018, 06:18:26 PM
Hi Nik2502

Do you take the vaginal progesterone all the time and if so how long have you been taking it like this? Did you notice a change in symptoms after starting it?

Hurdity x
Title: Re: Evorel 75 - need more?
Post by: Nik2502 on November 05, 2018, 08:21:14 PM
Hi Hurdity
I take utrogestan 7 days of my cycle as I'm sensitive to progesterone.
I've been on a combination of Evorel 75 and 100mg utrogestan vaginalkt for three months.
The dip started before I took the progesterone this month.
Nic x
Title: Re: Evorel 75 - need more?
Post by: Robin on November 07, 2018, 07:17:19 PM
Good luck for tomorrow Nic x
Title: Re: Evorel 75 - need more?
Post by: Nik2502 on November 07, 2018, 07:45:54 PM
Thanks robin. I'll post how I get on x
Title: Re: Evorel 75 - need more?
Post by: Nik2502 on November 08, 2018, 01:53:50 PM
One word. Pointless! Very pro Mirena even though I had horrific experience with ectopic pregnancy and coil a few years ago.
Basically I'm too fat and losing weight is the only other thing that will help. I didn't need to pay £120 to find that out!
I feel like a second class citizen where health professionals are concerned. I'm not diabetic, I don't have high BP, I live a relatively healthy lifestyle but I've always been big. I don't see why I have to suffer x
Title: Re: Evorel 75 - need more?
Post by: Yorkshire Girl on November 08, 2018, 02:35:48 PM
Hi Nik so sorry to hear this. No you should not suffer, it should not matter whether you are on the big side, slim or middling, everybody deserves to have help through the rollercoaster that is the menopause. It takes time & usual different treatments to find the one that suits. I really do hope you find someone who will listen and help. Sorry I can't be more help xx
Title: Re: Evorel 75 - need more?
Post by: Nik2502 on November 08, 2018, 04:19:39 PM
Thanks. It's just so annoying as it's not like anything they say is a surprise! I didn't think I was 10 stone this morning 😂
I'm put off with the Mirena and I think I'd rather use continuous utrogestan.
Like you say it's hit and miss until you find what works for you x
Title: Re: Evorel 75 - need more?
Post by: Hurdity on November 08, 2018, 08:19:17 PM
Sorry to hear you had a bad experience with the gynaecologist. Anyway 10 stone isn't THAT fat - depending how tall you are/frame size. If it were me it would be far too fat as I am short, but I can't see that a few pounds overweight or even a stone should stop the consultant prescribing or considering appropriate HRT.

Of course we should all aim for a healthy BMI and that is the best thing we can do as we reach this stage in life however big we have been - because this will help protect us from diseases of later life eg diabetes and heart disease which could develop later, but you can't lose that stone or whatever it is overnight - and in the meantime you want to be able to get help through this difficult stage - even while you might be deciding to tackle those pounds little by little! Great that you have a healthy lifestyle (good diet, plenty of exercise, no-smoking, minimal alcohol etc) and as you say aside from weight this helps to put you at lower risk from various conditions.

Does this mean you have not been advised about any different treatment nor has testosterone for example been suggested? What have you arrived at now?

Hope you start to feel better soon and try not to let this setback get you down!

Hurdity x
Title: Re: Evorel 75 - need more?
Post by: Nik2502 on November 08, 2018, 10:30:55 PM
Hi Hurdity
Sorry my post maybe wasn't clear. What I meant was she told me I was fat like I'd be shocked - I hadn't woken up ten stone and put ten on driving down!

All she suggested was having a Mirena which I don't want. In fact I think I did most of the talking!
It definitely wasn't worth the four hour round trip and £120.

I mentioned testosterone and she said absolutely not as it would make my skin dry?!

So I'm still on Evorel 75 with utrogestan 100 days 15-26. But she said if I refused a Mirena then it should be every day.

Feel more confused to be honest!