Menopause Matters Forum

Menopause Discussion => Alternative Therapies => Topic started by: Duffy on January 10, 2018, 09:57:46 PM

Title: Internal prometrium as part of hrt
Post by: Duffy on January 10, 2018, 09:57:46 PM

Anybody used their prometrium as a vaginal insert as part of hrt regimen.?  If so, what dose, what's schedule?  Any side effects to know about

Title: Re: Internal prometrium as part of hrt
Post by: Hurdity on January 14, 2018, 10:48:25 AM

Hi Duffy

YOu post got missed as it's in the "Alternatives" section. We don't have Prometrium here but if it's the same as utrogestan (oral progesterone capsules 100 mg/200mg) then some women use it vaginally off-licence as part of hRT. The dose is  200 mg x 12 days  per 28 for cyclical hRT and 100 mg continuously (or with 3 days break) for continuous combined (no bleed) HRT. De[ending on your dose of oestrogen you may need more or less - under medical supervision. There are fewer side effects when used vaginally because it aovids the "liver first-pass effect" where it has to be metabolised by the liver first before being used by the body - this produces many metabolic by-products which can cause side effects. The dose can be lower when used vaginally, or the cycle extended (under medical supervision) if you are post-menopause or late peri, because research has shown that more of the progesterone gets to where it is needed.

Hurdity x