Menopause Matters Forum
Menopause Discussion => Postmenopause => Topic started by: FranJF on January 04, 2026, 04:05:53 PM
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Does anyone use Prasterone to control their vaginal atrophy instead of topical oestrogen?
I'm 66 and had VA diagnosed last August. I have vaginal soreness but my real problem symptom is the constant need to pee. I'm up 5 or 6 times each night and trying to have a normal life is impossible.
I use Vagirux internaly and estriol cream for the soreness but neither have improved the urinary frequency.
I've read that Prasterone ( DHEA) can be helpful for urinary problems so I'd be really interested on hearing your Personal experiences. Thanks.
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Important question: how often are U using the products and adding that many do not get on with Vagirux which is cheaper to dispense than Vagifem.
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Hi CLKD,
I was using Estriol for 3 months, but only on the prescribed twice weekly dose after the initial loading period.
I'm now starting on my 2nd month of Vagirux which I'm taking daily. I expected to see some consistant improvement by now but I'm relatively ok(ish) one day and then back to being utter rubbish the following day.
I follow a very healthy diet, cutting out any potential triggers, don't smoke or drink and try to keep fit...not easy now as I need to stay near a toilet all the time. I'm desparate and miserable which seems to be a common theme with this horrible condition.
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As you are just starting your 2nd month you may need to give this more time & assess things after 3 or 4 months of use.
4 weeks use is likely not long enough but you do mention some days of improvement so that’s a start.
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In the early days of my va testosterone stopped it but I had muscle weakness as well, presumably including weakness of the pelvic floor. If you don't I don't know if it will help but worth a try. Topical oestrogen twice a week didn't sort it out either. My GP wouldn't prescribe it more often so I have gone down the Newson route instead and use more systemic oestrogen than the NHS will allow me. Mine was continual leaking rather than urgency.
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As always, thank you for replies.
Sheila99, are your symptoms under control now and how long did it take for you be comfortable?
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Yes, under control now but currently on 150 mcg oestrogen and tostran, no topical oestrogen. I can't remember accurately how long it took but I think about a month. Topical oestrogen didn't solve it for me but I was only allowed the daily loading dose for 2 weeks which wasn't enough, on 100mcg patch at the time. If your va is very bad sometimes the cream seems to absorb better than the pessaries.
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Glad to hear you have it under control, Sheila99.
I'm not on systemic hrt but I have another appointment at the end of this month so I'll discuss all my options then. Thank you
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I've been using Prasterone for about 3 months and have definitely had some improvements with my bladder, that was until my oestrogen levels dropped (I'm on the e implant). Before Prasterone I was using Vagifem 5 nights a week as well as Ovestin externally. Since you take it every night it really helps with dryness. I would recommend giving it a try but you may also have to try and increase your oestrogen levels to get some control over your bladder. I hope you find some relief soon, it really is horrible.
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Thank you Ayra underfoot
That is very useful information and something to discuss with the consultant.