Menopause Matters Forum
Menopause Discussion => All things menopause => Topic started by: Apple on September 25, 2025, 11:14:51 AM
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I'm on Kliovance systemic HRT and Ovestin cream. I've been using Ovestin externally for a couple of years. This year I had a urine infection in April and now just finishing treatment for another one.
I didn't realise the role of Ovestin in urinary issues until now. I've started to use it as instructed in the leaflet and doing a two week loading period internally intending to go to a couple of times a week after. I'm on day 5 of loading. Has anyone else found that Ovestin makes the area around the bladder sensitive? I feel like I want to go to the loo frequently but urine infection is now clear. Is this typical of the loading period with Ovestin?
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Hi,
I don’t know if it is typical but I have had the same issue.
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It sounds as though it may be related then.
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Ovestin really irritated my bladder/urethra. I use the estriol 0.01% cream internally instead and have no issues with that.
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I had all those weird sensations and it was estriol cream that stopped it. I had to use it for quite a while though and daily
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Sometimes the body can be sensitive to the fillers/packaging rather than the active ingredient which is of course, natural - oestrogen.
There are several different products to treat vaginal atrophy which can mimic urine infection-type symptoms really really well.
Perhaps it's tie to try Vagifem?