Menopause Matters Forum
Menopause Discussion => Personal Experiences => Topic started by: juliaC on September 01, 2025, 02:00:01 AM
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I'm at that mid point on evorel sequi where I need to change from pure estradiol to combined.
I am wondering whether to take Utrogestan instead this time and stay on Evorel 50.
My question is can you take Utrogestan with Evorel 50? Or do you have to be on Evorel 100?
I feel at my most well at this point and when I start the combined patch I start to go downhill with numerous symptoms. By the time I switch back to estradiol only I am physically at a very low ebb and it takes until now to feel normal again. So this time I thought I'd try Utrogestan again.
Does anyone know if it can be taken when you are on a lower dose of estradiol, Evorel 50? I will ask the doctor, they want me to change from Evorel Sequi anyway due to my age, 55.
Thanks
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Yes you can use Utrogestan with an Evorel patch.
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With the 50 mcg patch the standard utrogestan dosage is either 100 mg daily or 200 mg for 12-14 days if taken sequentially.
I tried both of these regimens multiple times, while being on the same dose of estrogen, so I’m 100% sure. (I’m progesterone intolerant, so I’m no longer taking utrogestan anymore, but trialing different progestagens).
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As you feel at your best when your own oestrogen is high (assuming you still have some ovarian function) it might be that you would benefit from a higher dose of oestrogen which would mean a separate progestogen anyway. The NHS is very good at telling you that you have to go on conti before your body is ready for it which then leads to unnecessary intrusive procedures for 'unexpected bleeding' when it might be your own period which is very much expected. They believe everyone is meno by 54 even though many aren't. If you think you're not meno it would be better to stay on sequi as conti hrt won't stop your periods. I'll get off my soapbox now ;D
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As you feel at your best when your own oestrogen is high (assuming you still have some ovarian function) it might be that you would benefit from a higher dose of oestrogen which would mean a separate progestogen anyway. The NHS is very good at telling you that you have to go on conti before your body is ready for it which then leads to unnecessary intrusive procedures for 'unexpected bleeding' when it might be your own period which is very much expected. They believe everyone is meno by 54 even though many aren't. If you think you're not meno it would be better to stay on sequi as conti hrt won't stop your periods. I'll get off my soapbox now ;D
Thanks, that seems to be what's happening doesn't it, if I'm feeling better bang in the middle of the cycle. I'll look into that.
Yes the doctor's surgery is causing a lot of people grief. It used to be good.
I should have taken the utrogestan last night but didn't as wasn't sure I could. I had some very mild period pain this morning, would bleeding start that soon from a short delay in getting the progesterone? Nothing yet but I'm full of energy (not me on the combined patch) and have that feeling it's imminent and it's not time, I don't think. Haven't been monitoring it ::)
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With the 50 mcg patch the standard utrogestan dosage is either 100 mg daily or 200 mg for 12-14 days if taken sequentially.
I tried both of these regimens multiple times, while being on the same dose of estrogen, so I’m 100% sure. (I’m progesterone intolerant, so I’m no longer taking utrogestan anymore, but trialing different progestagens).
thanks Konijntje
do you mind me asking what your intolerant symptoms were on utrogestan? I'm hoping I'll be ok on it this time, the first time I tried it I felt bloated but as it was instant it might have been nothing to do with that and I didn't give it a chance.
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Yes you can use Utrogestan with an Evorel patch.
Thanks Dotty :)
Have you used utrogestan? How have you been on it if so?
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I got very very low mood on utrogestan. I also slept very bad and had severe lower back pain that just kept getting worse the longer I took it. I also had bladder issues, everything in and around my pelvis just got weakened and that was probably the reason for the physical side effects. I tried taking it vaginally, but my bladder felt like I had an UTI when I did that and my sleep was obviously even worse, as I kept waking up to pee.
The low mood was the worst, but the physical issues definitely didn’t help. (I did sleep a bit better when I switched to taking the utrogestan in the afternoon). I tried to see if I could get used to it twice (for multiple months), so I’m pretty sure I’m intolerant, but I’ve read multiple stories from people that had to fight through the side effects for over 2 months, but then could tolerate. It’s why I did try a second time, since the first time I was on a pretty low dose of estrogen (I got really nauseous from estrogen at first, so started low and worked my way up to an average dose) and I also read that upping estrogen helps some people with tolerance.
So, definitely worth another try if you feel like you haven’t given it a long enough chance the first time.
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I got very very low mood on utrogestan. I also slept very bad and had severe lower back pain that just kept getting worse the longer I took it. I also had bladder issues, everything in and around my pelvis just got weakened and that was probably the reason for the physical side effects. I tried taking it vaginally, but my bladder felt like I had an UTI when I did that and my sleep was obviously even worse, as I kept waking up to pee.
The low mood was the worst, but the physical issues definitely didn’t help. (I did sleep a bit better when I switched to taking the utrogestan in the afternoon). I tried to see if I could get used to it twice (for multiple months), so I’m pretty sure I’m intolerant, but I’ve read multiple stories from people that had to fight through the side effects for over 2 months, but then could tolerate. It’s why I did try a second time, since the first time I was on a pretty low dose of estrogen (I got really nauseous from estrogen at first, so started low and worked my way up to an average dose) and I also read that upping estrogen helps some people with tolerance.
So, definitely worth another try if you feel like you haven’t given it a long enough chance the first time.
Thanks, now I'm not sure about it haha
On the combined patch I get that feeling that my pelvic area, all around including lower stomach gets weakened. At the moment my pelvic area is so normal I don't want it to change, but it will it does every time.
I think there's a higher dose of utrogestan so I may be better off staying on evorel sequi, problem there is convincing the doctor.
I'll be fine on the combined patch for the first week, but the second week the problems start, plus I swear I eat mountains of sugar then as well for energy.
By the time I'm back on estradiol patch only my teeth are tingling (as if they've weakened!), my skin on my face feels thinner, my pelvic area can't fight gravity and it takes two weeks on that for all this to disappear.
I wish you well trying out other progestogens. I might just put on my conti patch for now, and think through this again next time when hopefully the doctor has got back and I can afford a private clinic. :-\
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Hi JuliaC. I’ve used Utrogestan continuously for 7 years. I’ve been fine on it, except for episodes of break through bleeding.
Remember there are many woman taking Utrogestan who don’t come on these forums because they done have any problems.
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If you have evorel conti you have no option except to be on conti. If you have patches with utro the overall dose and therefore the prescription is the same whichever you're on so you do have the option to stay on sequi. I didn't get on well with utro either but most people are fine, and there are probably more who don't tolerate norethisterone than utro.
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If you have evorel conti you have no option except to be on conti. If you have patches with utro the overall dose and therefore the prescription is the same whichever you're on so you do have the option to stay on sequi. I didn't get on well with utro either but most people are fine, and there are probably more who don't tolerate norethisterone than utro.
Thanks, so it's worth a try with Utro. I was fine on norethisterone at first, felt better on it, but that was 3 years ago.
Unfortunately a gp has told me I cannot stay on evorel sequi as it's 'not safe' at my age. I could see another gp but it's virtually impossible to see anyone at the surgery currently anyway unless urgent. So private it will have to be when I can spare the funds.
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I do wish they would stop talking sh*t. You catch them lying once and never believe them again. It's only 'not safe' if you allow your lining to build up. And it's time they admitted the 'every woman is meno by 54' mantra is a pack of lies. You may be fine on conti but if you're not because you still have your own cycle there's no need to go private if you're on utro, you can use the same prescription and they'll never know.
The nhs meno clinic specialist agreed I could stay on sequi at 62ish and I'm assuming she knows more about safety than a gp.