Menopause Matters Forum

Menopause Discussion => Postmenopause => Topic started by: bagsbysyl on May 23, 2025, 02:16:31 PM

Title: Estradiol patch
Post by: bagsbysyl on May 23, 2025, 02:16:31 PM
My question is has anyone in postmeno experienced low estradiol with norm T and P and still had extra weight in midsection and thighs? I am wondering if I need to have my doc bump up my dose. I workout daily and eat 95% clean diet with high protein. I have only been on for 8 month and I know it can take time.... I feel good other than the weight and still low libido :(
Title: Re: Estradiol patch
Post by: bombsh3ll on May 23, 2025, 03:17:18 PM
Body shape is not a suitable metric to gage whether the dose of hormone therapy is therapeutic or not.

Personally in the absence of symptoms I will be aiming for a minimum of 400pmol/L estradiol for bone and cardiometabolic health. This approximates the average level across a healthy menstrual cycle, leaving out the ovulatory peak.

If I was at this level and still symptomatic, I would increase further, however I wouldn't personally want to be above around 800-1000pmol/L long term.