Menopause Matters Forum
Menopause Discussion => All things menopause => Topic started by: K45 on December 19, 2024, 01:09:03 PM
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Hi ladies,
If anyone has Gilbert's syndrome and is on hrt -be careful! Saw GP & my bilirubin has increased quite a bit after starting estradiol gel back in March. Previously I thought gel wouldn't affect the liver but apparently it is still processed the same. Explains a lot! I've now been advised to drop to 1 pump. Is one pump and 100mg progesterone daily still fine? Will this likely mean less or more bleeding? Big thanks to those who suggested continous progesterone as oh my goodness I literally haven't broken down in tears once since stopping the cyclical approach. Going from feeling suicidal every 4 weeks it's quite unbelievable how one tweak can make such a difference! X
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Who is overseeing the 'Gilbert's syndrome? MayB it's time to get an appt for a dedicated menopause clinic?
Your body will let you know if your new regime is enough.
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I was on 1 pump plus 100mg of Utrogestan daily for the 20 mths I was on HRT and never had any problems.
I also have Gilbert's Syndrome but interestingly the only time my bilirubin level has been within normal range was in a blood test I had in Aug when I had been on HRT for 18mths.
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Flowerpoint - Glad to hear you were okay on one pump- that's very reassuring indeed as 2 pumps is way too much so hopefully one pump will be ok...
Very interesting that you were in normal range being on a lower dose of hrt- I read somewhere that it depends upon how many genetic mutations you have in terms of whether you're ok with detoxifying oestrogen.
CKLD - gp is much only option who is very supportive and come up with a few suggestions things a bit more manageable. No menopause clinics as live in a very remote area unfortunately!