Menopause Matters Forum

Menopause Discussion => All things menopause => Topic started by: Lisasmith on July 16, 2024, 11:55:33 AM

Title: Continuous progesterone question
Post by: Lisasmith on July 16, 2024, 11:55:33 AM

Does anyone take 200mg progesterone, vaginally, continuously? This is what I’ve been advised, but when I google, it says taking it vaginally is off label, so I’m concerned it isn’t tested fully, and may not be as safe as taking it orally? Taking 200mg orally is too much for me, and if I take only 100mg I have on and off heavy bleeding. For context I’ve been on HRT about 8 years - had no bleeding with the Mirena but I don’t want another of those.

Title: Re: Continuous progesterone question
Post by: CLKD on July 16, 2024, 11:59:11 AM

 :welcomemm:

hopefully some1 will be along. However, many medicines are offered 'off label' because they have been found to work.

Title: Re: Continuous progesterone question
Post by: sheila99 on July 16, 2024, 12:34:31 PM

It seems to be a licensing issue rather than a medical one. In the rest of Europe utro is licenced for hrt orally and vaginally. In the UK it's  licensed for hrt orally but ivf vaginally.

Title: Re: Continuous progesterone question
Post by: Polpringle on July 16, 2024, 01:04:01 PM

I’ve been using 200 continuous vaginally for the last 2 weeks without a problem I  insert one about 3pm and the other at bedtime, obviously as it’s off licence I have no idea if that’s ok but so far it’s working for me

Title: Re: Continuous progesterone question
Post by: bombsh3ll on July 17, 2024, 05:04:48 PM

I used utrogestan vaginally 12 years ago during IVF and only heard of it being used orally much more recently when I became interested in menopause.

I couldn't believe people were swallowing the same capsules that I used to stick up my chuff.

It has been used this way for years and if it were at all unsafe it wouldn't be used in IVF and early pregnancy.

If it works for you that's great.

Title: Re: Continuous progesterone question
Post by: Cassie on July 17, 2024, 06:10:42 PM

I thought it was 100mg used continuously and vaginally is fine, if it doesnt cause you irritation. I prefer it this way. 200mg daily is a very strong dose how much oestrogen are you using?

Title: Re: Continuous progesterone question
Post by: Polpringle on July 17, 2024, 08:16:39 PM

Quote from: Cassie on July 17, 2024, 06:10:42 PM

I thought it was 100mg used continuously and vaginally is fine, if it doesnt cause you irritation. I prefer it this way. 200mg daily is a very strong dose how much oestrogen are you using?

I think it’s the new rules of 4pumps and upwards 200mg is needed, that’s what my dr said

Title: Re: Continuous progesterone question
Post by: bombsh3ll on July 18, 2024, 05:22:21 PM

I was on 200mg three times a day from the embryo transfer until the end of the first trimester.

It didn't cause me any problems at all and is widely used in this manner for IVF.