Menopause Matters Forum

Menopause Discussion => Postmenopause => Topic started by: Kady2022 on July 24, 2022, 09:14:42 AM

Title: Genetic balanced translocation
Post by: Kady2022 on July 24, 2022, 09:14:42 AM
Hey ladies I know I’ve asked this before but I’m desperate to find someone who something similar!

So I’m a carrier of a balanced translocation between one of my X chromosomes and one of my 7s chromosomes which could results in my baby either having too much or too little genetic information and it would most likely result in either a miscarriage or a possibility that my baby having both significant developmental and health problems

Does anyone know if this can bring on early menopause I have all the sytmpoms of it and I have also done several menopause tests in which they have tested my FSH levels and they are all positive I’m just desperate to find someone who may have something similar
Title: Re: Genetic balanced translocation
Post by: CLKD on July 24, 2022, 12:10:39 PM
You have a couple of threads on the Forum, why begin another  :-\

You won't find out more by repeat posting.
Title: Re: Genetic balanced translocation
Post by: Kathleen on July 24, 2022, 12:53:20 PM
Hello Kady2022.

I am afraid that I can't help you with your query  but have you considered emailing Dr Heather Currie who established Menopause Matters? She may have information or contacts that would be helpful to you. I understand that the emailing service costs £30 and is available through this site.

I hope you find the answers you are looking for and please let us know how you get on.

Wishing you well.

K.

Title: Re: Genetic balanced translocation
Post by: Uptick on July 24, 2022, 01:34:21 PM
Hi Kady, all FSH tests will be positive. You need to go to your GP and ask for FSH and estradiol blood tests. This will have to be repeated in 2 to 4 weeks. If estradiol is consistently low and FSH consistently high, you will be diagnosed with Premature Ovarian Insufficiency and your GP will prescribe you HRT. The fact that you have a genetic translocation doesn't change that, but it is a good reason to perform the tests IF your GP is reluctant.
Title: Re: Genetic balanced translocation
Post by: Uptick on July 24, 2022, 01:37:09 PM
You have a couple of threads on the Forum, why begin another  :-\

You won't find out more by repeat posting.

Kady might find out more, CLKD. Not everyone knows how to navigate the forum boards and posts get missed.  ;)
Title: Re: Genetic balanced translocation
Post by: CLKD on July 24, 2022, 01:42:29 PM
Not if 1 keeps to one thread about a subject, that is why 'unread posts since last visit' is the button to press each time a member visits the Forum.

 There is a danger of 'not again' so people stop reading.

I don't think that there will be many responses due to the complexity which you have pointed out.
Title: Re: Genetic balanced translocation
Post by: Limpy on July 24, 2022, 02:21:53 PM
CLKD - Kady is a comparatively new member on MM  it might be nice not to bully her.
Are you a moderator on MM?

Title: Re: Genetic balanced translocation
Post by: CLKD on July 24, 2022, 04:58:14 PM
Be kind ?  I can't get a reply as to why more than 1 thread on a topic is necessary. 

It is becoming common across the Forum by many members, instead of continuing in a thread so that women can scan down to previous replies, after all - many of us suffer with memory problems due to hormonal upheaval. 
Title: Re: Genetic balanced translocation
Post by: Limpy on July 24, 2022, 06:05:26 PM
Be kind ?  I can't get a reply as to why more than 1 thread on a topic is necessary. 

It is becoming common across the Forum by many members, instead of continuing in a thread so that women can scan down to previous replies, after all - many of us suffer with memory problems due to hormonal upheaval.

That's exactly it CLKD - many of us can not remember what we have posted and where!

Title: Re: Genetic balanced translocation
Post by: Uptick on July 25, 2022, 01:30:54 PM
Hi again Kady, I hope you can sort it soon. I'm sure there are other woman out there with the same questions, balanced translocations are very common amongst cases of infertility. Maybe you will have more replies on forums like mumsnet. Keep us posted.
Title: Re: Genetic balanced translocation
Post by: Kady2022 on July 25, 2022, 03:49:24 PM
Hi again Kady, I hope you can sort it soon. I'm sure there are other woman out there with the same questions, balanced translocations are very common amongst cases of infertility. Maybe you will have more replies on forums like mumsnet. Keep us posted.

I’ve tried Mumsnet and nothing
Title: Re: Genetic balanced translocation
Post by: Marchlove on July 25, 2022, 04:08:41 PM
Hi Kady

There’s a website called fertility friends forum, you could try on there perhaps? X
Title: Re: Genetic balanced translocation
Post by: littleminnie on July 25, 2022, 05:38:52 PM
Hi Kady.   Check out Facebook see if there any groups on there. 
Title: Re: Genetic balanced translocation
Post by: Kady2022 on July 25, 2022, 07:52:32 PM
Hi Kady.   Check out Facebook see if there any groups on there.

I have but not sure if I’m searching for the right thing
Title: Re: Genetic balanced translocation
Post by: Marchlove on July 25, 2022, 07:58:19 PM
Hi Kady

Yes I think you’re right, you should rethink your search terms.
When I had a quick Google I put in specific  words that you had used and quite a bit came up.
X
Title: Re: Genetic balanced translocation
Post by: Uptick on July 26, 2022, 07:36:28 PM
Kady, you can see here https://www.menopausematters.co.uk/pm-investigations.php (Menu on the left 'Menopause' > 'Premature Menopause') the clinical procedure for cases like yours. I'm sure you can tell your GP to do the same, if s/he is not familiar with premature menopause.
Title: Re: Genetic balanced translocation
Post by: Marchlove on July 26, 2022, 08:18:55 PM
Thank you for helping with Kady’s issues Uptick.
Uptick is one of our very knowledgeable forum members Kady, so I’d trust her directions for your journey ahead. xx
Title: Re: Genetic balanced translocation
Post by: Uptick on July 28, 2022, 11:07:02 PM
Hi Marchlove, thank you, you're very kind, but I'm not knowledgeable, I just know where to find reliable information. Let's hope Kady has managed to talk to her GP.
Title: Re: Genetic balanced translocation
Post by: Bindi on July 31, 2022, 11:59:19 AM
Hi kaddy
Im julie i have a genetic translocation to hun its of my chromosomes  20 and 21 i am a carrier aswell and have passed it on to my some of my children and gramd children without knowing...Is scarey when you find out hun i was devastated but research   is a good tool.. if you would like to chat let me know..