Menopause Matters Forum
Menopause Discussion => All things menopause => Topic started by: sweettooth on April 13, 2022, 08:38:28 PM
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Hi ladies,
Anyone have experience in splitting dose to from all in morning to morning and night?
I’m on 2mg tablet and find my mornings very difficult. I take my 2mg at 9am and feel better as day goes on though by no means smooth until after 5 or 6pm.
Would it help if I took 1mg at 9am and 1mg at 9pm? Thank u
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Hey sweet tooth, no harm in trying the split dose.
Which tablet do you take?
I’m going to try the same.. got to get more o into my body somehow, as bladder will self combust!!
Best of luck x
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I would expect it to level out the fluctuations a bit. No experience with tablets but I split my gel this way, many others do too (though originally because I ran out of skin).
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Hi Nas, so sensitive to fluctuations and the 2mg (Estrogen only)suited me taking it all at once in the mornings but that was before covid vaccine and since then Iv been unstable, I did have periods of increasing and decreasing so probably taking longer to become stable again.
Tried extra and felt worse so that’s no good. Maybe it’s a matter of waiting for all to settle again I just don’t know! Drives me crazy tbh! Had an awful morning but it improved thankfully by 5pm. Long day to suffer. Every morning my body is so unsettled, I’m low and legs are weak (same as pre hrt) then it improves as day goes on, so that must be after my Estrogen tablet. What a maze this is🙄
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A thought is that somehow post vaccine your morning cortisol levels have altered. Cortisol is supposed to be high in the morning, whether yours are now too high or low is difficult to know without saliva testing.
Oral estrogen is known to alter cortisol levels to a greater degree than transdermal from what I’ve read.
So what to do, I think it would be trial and error.
You could try splitting the dose for a few days
If that doesn’t work you could try just taking it in the evening, either full or just half dose.
Do you feel able to trial this sweet tooth? xx
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I'm trialling splitting my oestrogel dose, it's only been a few days but so far it seems ok. Maybe taking some at night will help you with the morning 'dreads'. I find if I ever get that morning cortisol/ adrenaline feeling it helps if I tell myself that's all it is and then try not to pay it any attention. It seems to go away quicker if I don't buy into it. Not sure that makes sense, but I think it helps stop me being frightened of it which is the worse thing for me as it then escalates. As Marchlove says, give it a go, but I would add that if you do decide to do it then stick it out for a while because there is could be a bit of an adjustment period.
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Hi Sweettooth. You could certainly try splitting the dose, I used to do this. However now I take my tablet just before bed so that everything has time to metabolism overnight and so that I feel fine in the morning. I find I sleep better taking the tablet at night too as I don’t have the early morning waking any more. It might be worth a trial to see if it helps you.
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Hi ladies thank you so much for all your lovely replies! I’m finding it extremely difficult since vaccine, before that tablet worked a dream!
I think it’s def worth a try from what you say but might leave it just until I feel a bit stronger. Interesting re the cortisol, after my vaccine last year my heart raced every morning for months, my body was on complete overdrive!
Sheer suffering. I’m too afraid to switch to transdermal at present. Nightmare :'(
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Floradora, can I ask what strength you’re on? I’m well post meno xx
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I’m now on 1mg conti sweettooth as I’m past meno . When I was on 2mg I used to split the dose as taking it all at once made me jittery. I actually feel much better and more stable on a lower dose now anyway. X
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That interesting Flora! Did you taper to get to 1mg? Apart from feeling jittery did you have any other symptoms of too much? Sorry re all the Qs x
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No I didn’t taper sweettooth, just went straight from 2 to 1mg. On 2mg I frequently felt nausea and dizziness and just very bloated. Took me a long time to work out that it was probably too high a dose of estrogen that was the problem. All those side effects disappeared immediately and fortunately I didn’t get any hot flushes, night sweats etc returning after dropping to the lower dose. I do have to take vagifem/ ovestin etc and keep on top of that as 1mg doesn’t really keep the vaginal symptoms down but I’d rather do that than than have the higher dose of estrogen now . Sometimes if I get a flare up of vaginal symptoms I’m naughty and do a few days of double dose of tablets- but not often now. For me definitely a higher dose isn’t better. Unfortunately the symptoms of too much estrogen often are very similar to those of too little! So it’s just trial and error. Hope you feel better soon x
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Thanks flora much appreciated. I really don’t know. I am extremely sensitive to any changes so I’d have to do it gradually. I don’t get bloating or those things.
I will prob try either splitting the dose or taking the 2mg at night first.
Felt great b4 vaccine so maybe it’s taking time for my body to recover. Tks again glad you are doing well xxx
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If I were you I’d maybe try taking your tablet before bed. That way you can wake up with a good amount already in your system from overnight and won’t have to try and get through the day waiting to feel better. Hope you get a change that works soon x
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Thinking same as you Flora. You’re v kind to reply, thank you! I’d do anything to feel better it’s just awful. I got covid to add to the mix and although the actual symptoms were not that bad, it has messed things up that were improving. Sure is challenging!! X
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Good luck, sweet tooth.
I’ve never found anything so difficult to fathom as HRT to be honest.
I’m sure your body will settle over time. I’ve read about a few ladies who have experienced a return of symptoms, after the covid vaccine. Hang on in there I would!
I’m also going to trial my tablet a night time also. Anything is worth a shot, there’s no harm in experimenting.
Floradora, did the double dose of tablets fix the vaginal issues?
I’m on the 1mg Conti but struggling with a bad flare of bladder problems, despite using vagifem and ovestin.
The temptation is to take 1mg am and pm right now!
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Hi Nas. Yes I find if if I do a double dose am and pm for a couple of days together with a double dose of vagifem and ovestin etc that usually helps get on top of a flare up. I feel for you, the VA symptoms are just dreadful and hard work to keep under control. However I find the 1mg conti regime far better for everything else for me so it’s just a trade off really. Have a go with taking your tablet at night too. Anything is worth a shot and I always find that I can cope with any symptoms far better during the day rather than in a panic at 5.00am. Another plus of changing to take my tablet at night is that I rarely have to get up to pee and previously I was up twice a night! 😂
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Thanks Flora,
I’m having such a rough time with the bladder, it’s making me despair!
Two weeks ago, I broke up for the spring break ( I work in a school) with horrendous issues. Fast forward and I’ve still got them! Back to work Tuesday and I don’t want them then!
Took my second Conti tonight, plus vagifem x 2.
Going to do that all weekend and see what happens.
It’s pure hell.
Xx
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Yes give that a go Nas as a few days of vagifem may help to get on top of things. Unfortunately worry and anxiety about bladder issues makes an irritated bladder even worse doesn’t it. I do hope you get a good sleep tonight. Maybe a nice hot water bottle and a couple of nurofen might help too. Sleep well x
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Thanks for being so kind flora.. really appreciate it.
Sleep well too xx ❤️
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Nas so sorry to hear you are having bladder issues on top of all this other stuff, it’s so unfair! Do u mean cystitis? Sorry but what are your symptoms? Can’t even enjoy your term break. As flora says anything is worth a try. Perhaps pro biotics would help too?
I’m trialing 1mg this morning and 1mg tonight then maybe do my 2mg at night so that my mornings are more bearable.
I woke this morning with awful racing heart and I’m on a high dose beta blocker since vaccine! Sometimes feel I can’t go on but thankfully that doesn’t stay🤞
I have found my meno symptoms worse again since having Covid 3 weeks ago, it’s never ending. Gosh I’m so willing all of us on here struggling have better days ahead🙏🏻🙏🏻 Xx
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Hi sweettooth,
It’s a hideous journey isn’t it?
I was a member of a Facebook menopause group and there were a few ladies on the oestrogen tablet with a history of BC ( did you mention you had a diagnosis at some point ? Apologies if not 🤦♀️)
Anyway, they all reported a return of symptoms following the covid vaccine. It took them a while to feel better again, but it happened. Hang on in there! I feel sure you will improve, give it time. Do you take propranolol? It can be good for a racing heart.
My bladder has been very irritated, weeks into starting the 1mg tablet. It’s not cystitis, but a general “ irritated” feeling with frequent need to wee. Stinging a bit now too 🤦♀️
I’ve got some meds to pick up tomorrow to hopefully calm it down a bit. I had it pre Hrt but my patch and vagifem sorted it.
I came off the patch due to bleeding ( but don’t know if Its period or hormones causing it, another dilemma!!)
Anyway, enough of my woes.
Really hope you feel better soon sweet, none of us deserve this hell xxx
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Hi Nas,
Do you feel mood etc better on tablet Estrogen? Glad you at least have meds to pick up to help it! I’m sure it will settle, I’m thinking of you.
Yes Nas I do have bc history, this is another scale, I’m sure you would agree.
I was starting to see improvements Nas since being affected by jab but then got Covid almost 3 weeks ago and hormones bad again. I am on high dose proprananol since vaccine. Yes I am clinging on like so many lovely ladies on here yourself included. Let us know how your treatment goes🤞🤞
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Hey sweet, yes I think mood is stable on the tablet.
I prefer it to the patch as no sticky marks on bum or worry of them peeling off etc. If only I could get the dose right! 2mg is a bit high for me, but I reckon 1.5 would do the job. Now to work out how to get the extra 0.5mg as they only come in 1/2mg tablets. I don’t have a review for a few weeks, so may have to wait and persevere with 1mg for now.
Having a BC history has really made the whole treatment of meno doubly hard in truth. It’s been a constant battle to be heard!
Wishing you well too xx
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Nas if u do decide to do 1.5 just get a pill cutter and cut 1mg in half. Take care x