Menopause Matters Forum

Menopause Discussion => All things menopause => Topic started by: 2cats on December 24, 2013, 04:23:04 PM

Title: Progesterone and mood
Post by: 2cats on December 24, 2013, 04:23:04 PM
HI ladies,

I've been on estradot 50mcg every day and cyclogest 200mg pessaries for 2 weeks out of 28 days for approx 2 cycles.  Everything is going ok but for the fact I feel my mood is dropping a few days after I stop using the progesterone...could this be the case??

I'm finding that I'm counting down the days until I can start using the cyclogest again.  I've no idea where I am in the menopause, but would I be able to take it for longer in the month?

Any advice would be most welcome,
MErry XMas :)
Title: Re: Progesterone and mood
Post by: Suzyq on December 24, 2013, 05:39:29 PM
I'm exactly like that! My specialist told me I can take 2 applications of progesterone (I'm on bio-identical) for 2 weeks, then carry on with 1 application for the other two weeks. I also felt terrible when I had to stop taking it
Title: Re: Progesterone and mood
Post by: Cassie on December 24, 2013, 07:13:37 PM
Funnily enough, I am the opposite, but as I have said on previous posts, that seems to be the norm, where Progesterone makes most people sleepy, it makes me very hyper and where it may make most folk lovely and chilled, it makes me moody and bitchy, sigh!
Title: Re: Progesterone and mood
Post by: Hurdity on December 29, 2013, 11:34:32 PM
Hi 2cats

It is normal to feel a dip in mood or tension, irritability or headches for a few days after stopping progesterone - this is like classic pmt ie what happens just before a normal period when both oestrogen and progesterone levels drop.

It is the body's physiological response to the dramatic changes in hormones levels. You should find that once your body has eliminated the excess progesterone and you are back on the pure oestrogen you should feel really good again. This is known as progesterone withdrawal and can lead to a migraine or feel like a hangover - this always happened with me when on Cyclogest - some months worse than others. So it's not that you need progesterone to feel good - but you feel bad while levels fall and should then feel good again when you are back to oestrogen only, as your hormone levels will then be stable again.

For some women who are progesterone intolerant - they feel depressed or fatigued all the time they are taking the progesterone as well. However women who can tolerate the progesterone are lucky only to have the few days of "normal" pmt which it sounds like you are experiencing. You should have started to feel better from 3 days or so after stopping and when your bleed came ( if you had one this month).

The thing is there is often no magic solution where you will feel really good all the time - that would be wonderful! However hopefully you can find a treatment where you feel better for most of the time!

Hopefully you are now feeling really good again!

Hurdity x
Title: Re: Progesterone and mood
Post by: katyh75 on December 14, 2021, 11:44:55 AM
I'm on continuous progesterone 200mg as I don't tolerate 100mg (it makes me anxious and tearful).

I have only been on it for two weeks but I feel grotty and low.

Has anyone else on continuous experience this, persevered and had it resolve? The days feel very long currently!

Title: Re: Progesterone and mood
Post by: Jop4321 on March 21, 2022, 06:34:08 AM
Just wondering why gp has increased your dose from 100.g to 200mg if you weren't tololerating it well? I am currently on 100mg  tablet form and i feel grotty and ow with headaches and sometimes stomach issues. Think   im going to see if mirena coil hascless side effects
Title: Re: Progesterone and mood
Post by: katyh75 on October 26, 2022, 01:52:59 PM
I tolerate 200mg but not 100mg