Menopause Matters Forum
Menopause Discussion => All things menopause => Topic started by: Kathleen on June 24, 2016, 06:20:58 PM
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Hello ladies.
I've been thinking about the quantities of hormones that we use, specifically the Norethisterone in Evorel Conti patches and the Utrogestan in the capsule. It seems that one microgram is one thousandth of a milligram ( 1/1000). Therefore the progesterone in a 100mg Utrogestan capsule is about 500 times greater than the 170 micrograms of Norethisterone in an Evorel Conti 50 patch. Are you still with me? The point I am trying to make is that if we take Utrogestan orally we are getting much more progesterone, albeit bio identical, than if we use a patch. I think others have queried why we can't get a lower dose of Utrogestan capsule as surely this would be a good idea! Could this be another reason why using the Utrogestan vaginally is preferable, simply because the 100mg dose is so high it overwhelms the oestrogen.
Sorry if this is long winded but I'm struggling with anxiety and palpitations atm and I'm looking for solutions. In the meantime I plan to use the Utrogestan vaginally tonight and see if that helps.
Just some thoughts ladies and I look forward to reading any comments.
Take care.
K.
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That's complicated :D because I don't understand sums :-\
Let us know how you get on!
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As I understand it utrogeston isn't as strong as say norethisterone say.
So if you imagine a basic supermarket orange squash and a really expensive squash you would need to put more of the undiluted basic orange in the glass to get the same results as the expensive one . Well this is the analogy that I use to explain it to myself,have I confused you more now ! ;)
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;D yep
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Hello dazned.
I think understand you, it's more about quality than quantity.
Thanks for that.
K.
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Progesterone is degraded very easily in the gut, liver and digestive system. So higher doses of progesterone is needed than with progestins.