Menopause Matters Forum

Menopause Discussion => Other Health Discussion => Topic started by: Iris67 on April 07, 2021, 11:46:23 AM

Title: Nitrofurantoin 5 day v 7 day course?
Post by: Iris67 on April 07, 2021, 11:46:23 AM
I was prescribed a 3 day course for an uncomplicated UTI....it failed to work. I have been prescribed a further 7 day course and I have take 5.5 days worth. It is making me very ill and my symptoms have cleared up. I want to stop (GP will advise protocol - finish it all) and I can't find any info on the efficacy of 5 v 7 days of this horrible drug. Anyone have a view?
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Limpy on April 07, 2021, 02:12:21 PM
I know this'll sound awful but really it is best to finish this course. Not to do so stands the risk of generating antibiotic resistance. It's possible that the 5.5 days you've managed may be enough but best check with somebody who knows. It might be worth speaking to a pharmacist and see what they say.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Katejo on April 07, 2021, 06:39:32 PM
I was prescribed a 3 day course for an uncomplicated UTI....it failed to work. I have been prescribed a further 7 day course and I have take 5.5 days worth. It is making me very ill and my symptoms have cleared up. I want to stop (GP will advise protocol - finish it all) and I can't find any info on the efficacy of 5 v 7 days of this horrible drug. Anyone have a view?
  A  urogynaecologist advised me that  all AB courses need to be at least 7 days. Anything shorter and the infection may not clear and could return.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 07, 2021, 07:17:45 PM
Was a fresh urine sample sent to a Lab for testing?  Otherwise ABs may not be necessary.

I would ask for appropriate treatment for vaginal atrophy.  Do read the 'bladder issues' and 'vaginal atrophy' threads 2 C whether your symptoms match: VA mimics urine infection-type symptoms really, really well!

When I have the 'need 2 P' feelings, I take 'nurofen' regularly as well as using 'ovestin' twice a week.  The pain relief relaxes the spincter.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Taz2 on April 07, 2021, 07:28:28 PM
Nitrofurantoin has never worked for me whether 3, 5 or 7 days. I've always had to follow it up with 7 days of good old amoxicillin. I would still say finish the course though.

Taz x  :hug:
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 07, 2021, 07:31:41 PM
I've rarely finished a course of ABs by mouth due to them making me very sick. 
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Limpy on April 08, 2021, 09:58:21 AM
I've rarely finished a course of ABs by mouth due to them making me very sick.

No wonder resistance to ABs is on the rise - it was you!  ;D
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Iris67 on April 08, 2021, 09:59:04 AM
These are really interesting comments - thanks  :)

I had a feeling that a 3 day course was not enough the first time around, and I also had a feeling that 'good old amoxicillin' was the one I should be having! I did have a lab test which confirmed infection and that I was on the 'right' drug which meant the subsequent 7 day course but who knows if it was fresh! Not quite sure what happens after it goes to the GP in terms of correct protocols. My GP used to be superb but they're a bit all over the place at the mo.

I was feeling so bad yesterday - very drowsy, sick, headache, fatigue and dizzy and probably did the worst thing...missed a day and feeling better today have started the last 1.5 days worth. CLKD I think I am in a similar boat to you.

I read some research papers on Nitrofurantoin and it appears there is quite a high failure rate for the 3 day course. They take a risk at our expense because the drugs are failing in more broad terms - resistance-wise. In fact the medical guidance for a simple, minor UTI is no antibiotics and just NSAIDS. I know the body can heal itself theoretically but if they go for ABs then it should be hefty, not a halfway house.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Iris67 on April 08, 2021, 10:00:49 AM
Meant to add - the failure for 3 day Nitro - 15-20%. Might be useful for anyone in the same situation.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 08, 2021, 12:40:34 PM
AB resistance is due to over prescribing World Wide: expedically for urine 'infections' when ladies have VA  >:(
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Dougalina on April 10, 2021, 07:43:13 AM
Not finishing a course is not a good thing to do, it does contribute to AB resistance, which is why the instructions always say to finish the course.

Over prescribing is another reason.

D.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 10, 2021, 08:13:13 AM
I wonder how much recent research is done into 'AB resistance' if 1 doesn't finish a Course?  It was better that I didn't finish them as I would have thrown myself off a cliff, feeling so sick.    Of course, in hospital they could be given by drip avoiding the nausea.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 10, 2021, 08:13:56 AM
How do U feel Iris?
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Iris67 on April 10, 2021, 11:04:36 AM
Hi CLKD - thanks for asking - so far so good. Took last dose yesterday a.m. and no pain when weeing since. It's tricky because the menopause/prolapse causes so many weird feelings I get stressed every other minute! But no pain atm... fingers crossed. I was never one to suffer a UTI or thrush for that matter but post meno it's all falling apart. V depressing.

There are so many variables I think the research is fairly basic. And of course modern medicine doesn't do much in the way of 'preventative' because most of the time any underlying factors contributing to it are not clearly understood. If doctors concentrated on turbo-boosting our immunity many of these problems would be gone.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 10, 2021, 11:27:36 AM
The nearest to 'turbo boosting' my system would be in a Lambourghini - then I would need a toy boy to pull me out  ::)

I find taking 'nurofen' regularly eases the need2P feelings. 
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Jemp on April 11, 2021, 02:28:13 PM
Nitrofuratoin makes me very ill. I always ask not to be prescribed this if I hand in a sample for testing.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Donna-paul on April 11, 2021, 04:17:02 PM
Please take the full 7 days course as I wouldn’t want you to end up like me with a Cuti embedded in my bladder. It’s coursed by these stupid 3 day course of antibiotics which will never get rid of an infection. Men get 2 weeks of antibiotics animals do to while women get 3 days!! Which now is causing a serious problem for many people where the infection in now deep embedded in the bladder and only treatment is high dose long term antibiotics. I’ve been in treatment nearly 2 years to get rid of it with the only NHS clinic in the uk.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Katejo on April 11, 2021, 04:36:13 PM
Nitrofuratoin makes me very ill. I always ask not to be prescribed this if I hand in a sample for testing.
Same for me. I prefer Trimethoprim. Usually works for me and no bad side effects.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 11, 2021, 04:49:22 PM
Donna-Paul - have you been admitted for high-dose ABs via a drip? which bypasses the gut and can be administered easier?
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Iris67 on April 11, 2021, 05:25:03 PM
Despite the stupid 1 day break I did take them all. So far so good. Have started some D mannose as a preventative for a while.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 11, 2021, 06:51:49 PM
Do U have a diagnosed UTI?

MayB consider using vaginal atrophy treatment?
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: sorbet on April 11, 2021, 09:40:52 PM
Hi , hope you’re all well and your UTI heals .
I’m sorry to hijack this thread  , I’m in agony with burning.
CLKD ,
I haven’t been on for a while , hope you’re well . I didn’t have prolapsed organs. Saw a pelvic floor physiotherapist and she said I’ve got pelvic floor dysfunction.
Saw this thread , have been having horrendous burning, as though there’s a chill pepper in my vagina or urethra.
I’m taking antibiotics, started 3rd lot now , but they’re not helping. I never know what’s a UTI, thrush or Vaginal atrophy. I do test positive for leukocytes, but I’ve read that can also be VA and thrush . No itching or discharge.
Even the glands in my groin have come up in sympathy.
I’m allergic to canestan and nervous to take Flucloxacillin as it’s heavy on the liver .
I haven’t been using vagifem for months , but think I’d better get started.
I can’t get to see a GP , it’s a mess isn’t it.
I’m nervous to stop the antibiotics but my instinct is they’re not helping.
Any advice greatly appreciated.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Limpy on April 12, 2021, 09:54:19 AM
It does sound like VA Sorbet.
Think you're right about restarting the Vagifem. Also it might help if you can get some Estriol cream as it seems to be more effective on the external vaginal area.
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Iris67 on April 12, 2021, 11:08:43 AM
CLKD Yes - sample sent to the lab
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 12, 2021, 12:30:16 PM
sorbet - get that 'vagifem' up there ASAP.  1 dose now, the next this evening.  As well as pain relief for 3 days.  A GP should not prescribe ABs on the off chance  >:(

Tnx Iris67 - any improvements?
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: Donna-paul on April 12, 2021, 12:52:42 PM
Donna-Paul - have you been admitted for high-dose ABs via a drip? which bypasses the gut and can be administered easier?
Yes and it is last resort as it wipes out everything and the bugs come back even worse these words from the specialist. It is so true as I have to have it when it goes to my kidneys and initially I respond straightaway 1 week to 2 weeks later is comes back even worse. The only way to get rid of a embedded Cuti is high dose long term antibiotics unfortunately .
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: sorbet on April 13, 2021, 12:46:34 AM
It does sound like VA Sorbet.
Think you're right about restarting the Vagifem. Also it might help if you can get some Estriol cream as it seems to be more effective on the external vaginal area.

Hi StongKat , I’m back on the Vagifem. I’ve got a GP telephone consultation in a week so will ask for the Estriol cream too . Thank you for helping. xx
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: sorbet on April 13, 2021, 12:52:38 AM
sorbet - get that 'vagifem' up there ASAP.  1 dose now, the next this evening.  As well as pain relief for 3 days.  A GP should not prescribe ABs on the off chance  >:(
Hi CLKD , I’ve had 2 lots of Vagifem already . I won’t be stopping it again thinking things are okay. This VA is truly horrendous. Ibuprofen helps with the pain.  I agree they’re wrong prescribing AB’s . Thank you xx
Hope you’re okay Iris and so sorry. xx
Tnx Iris67 - any improvements?
Title: Re: Nitrofurantoin 5 day v 7 day course?
Post by: CLKD on April 13, 2021, 08:44:03 AM
Morning.  When I had emergency surgery in 1991 - Valentine's Day  ::) - I had dreadful thrush for 2 weeks after.  Next time I had elective surgery I swallowed great spoonfuls of Greek LIVE yoghurt to line the digestive tract.  Worked 4 me.  I've heard it works after AB treatment too.  To encourage good bacteria.

Don't know how if delivered directly into a vein it causes more problems  :-\ as the medication by-passes the gut.  MayB try LIVE yoghurt, not 'natural' as that isn't necessily 'live'  ;).  3-4 large spoonfuls 3-4 times daily. Worked for my dog when she had heartburn  ;)