Menopause Discussion > All things menopause

Utrogestan used vaginally

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Hurdity:
No it doesn't seem to be heard of so much by GPs but it is a licensed product so it is up to us to educate them! Ditto my GP Stellajane!

Just remember anyone who wants to ask for it and the doc hasn't heard of it - to ask for "Micronised progesterone" because that is how it is listed in the magic book. That will appear on your prescription but you will get Utrogestan.

No not licensed for vag use in UK but is in rest (or some part) or Europe. I have the translation from the French SPC (product info) which I sent for from the manufactuers about 18 months ago. If anyone wants them I can pm it (if you can add attachments).

Hurdity x

Cassie:
When I originally asked my GP for it, his response was oh ok will give you two months trial, but I hope that I dont get into trouble with your Gynae, had never heard of it! My very clued up lovely pharmacist lady told me about it when I was looking for a more natural approach to  progesterone as the cream was not strong enough to oppose the oestrogel. And I have always used it vaginally, I know that orally, it would make me feel grotty, I get nauseous very easily. This method so much easier, just pop it in at night and sweet dreams :)

Gig:
I just wanted to update this after having read what my dr has said in his book on this.

He calls  bioidentical progesterone 'micronised'.  It can be given orally, vaginally, rectally ( ouch) or with a gel. He states that orally, 300mgs is needed to overcome the 'bypass' issue- meaning a lot of the product is lost via the liver, and this dose of 300mg may give unacceptable side effects for some women ( digestive.)  I don't know if this info. has been updated since the book was published because you all take 200mgs.

Vaginal pessaries he says are not licensed in the UK for use with HRT but can be used for PMS and infertility. I think they are licensed in France but they are a gel in a pessary and not a hard oral tablet.  Obviously this is not the same as using the tablet vaginally.  Tablets are not licensed for vaginal use in the UK - but again, if your GPs have said okay then they must be. 

Hurdity:
Hi Gig

Thanks - yes this is out of date - we have posted several times about these preparations. Those of us who use bio-identical prog have researched it quite a lot over the last couple of years or more - here it is again:

There are 3 main brands of bio-identical progesterone - you will see from my post below that somepreparations are referred to as micronised

Cyclogest - these are waxy pessaries/suppositories used for infertilty but prescribed by some GPs for HRT as endometrial protection - the dose usually given is 400 mg - but I feel this is too high for endo but because not licensed there is no other yardstick. My GP started me off with this after I couldn't tolerate Evorel sequi

Utrogestan - these are the micronised progesterone capsules (small oval shape containing the micronised prog suspended in arachis oil) which are licensed for oral use in UK. Usual dose 200 mg for oral use for sequi. 100 mg for conti ( 26 out of 28 days). As I have posted before on this thread and elsewhere it is licensed in France for V use but not in UK for HRT and there is quite a lot of research giving dosage for endometrial protection by V use (lower than oral because of uterine first pass effect ie goes straight to womb and not through liver)  although admittedly small trials.

I have also posted that I do have the French SPC if anyone wants them (translated) which I obtained from manufacturer.

Finally Crinone gel - not many women seem to use this and I don't know much about it but theroetically it is available but again not licensed for HRT in UK. It is now only available at a higher concentration - the lower concentration - probs more acceptable for meno women - was withdrawn a while back

We have discussed all of this before.

They are not tablets (Utrogestan) - because progesterone does not come in tablet form. Presumably something in the manufacturing process means it cant be done, which is why Femoston is dydrogesterone - not progesterone.

Some docs do prescribe it vaginally but probably only a very few - and the notable ones like Nick Panay and some of the private ones. I expect Dr Currie would too.

I told my doc I was using it V and she was OK with that although it does not say that on my prescription.

Not trying to be difficult Gig but we have covered a lot of this ground and are well up on it!! Also had some good Friday vino so a bit hurried!

Hurdity x

Gig:
  Not everyone has been on the forum for ages and read everything. Apologies if you find it irritating that I've posted things you and the others know already or , that I am showing my ignorance.

Will go away now. :)

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