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Author Topic: Utrogestan  (Read 112053 times)

Hurdity

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Re: Utrogestan
« Reply #15 on: December 03, 2011, 10:10:23 AM »

Hi Rivadan

Yes I felt like that when I first started taking the Utrogestan - it really does have the sedative effect that prog is known to have! My head felt just like that and I slept really deeply. I sort of got used to it after a while - and for me that was really the only side effect - a bit foggy headed, but not the migraine type of head - ie not the tension that for me comes with withdrawal of the prog (although not with the Utro - the first time anyway).

Hopefully you will get used to it and still be able to function - yes it's a very busy time on top of everything else!

I am very interested in the quarterly regime which some specialists ( including the Prof I gather) do not find favour with now - and I must see if I can find some recent research on this when I have a mo'...). Cacey interesting that your doc has prescribed this several times and would be interesting to find out where they are in meno and whether they have had any problems - or indeed whether she recommends a regular scan for them?

I would never risk no prog even with an annual scan - if it is deemed safe then quarterly sounds like the way to go for many prog intolerant women

Yes weird how we react to different chemicals and hormones and at different stages - no wonder we are all difficult to treat!

Have a great weekend

Hurdity x  :)
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coffee mate

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Re: Utrogestan
« Reply #16 on: December 03, 2011, 10:24:09 AM »

The last week or so I haven't been sleeping as well as usual [well -usual for me anyway] and it does seem to coincide with me stopping the Provera, that I used to take at bedtime.

So for now I am left with two choices - 1, erratic sleep patterns or 2, really bad PMT.
I think I made the right choice for now, as the PMT really does wear me out. I actually feel drained with it.
At least I can cope with less sleep. For now anyway.  :)
cm xx
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Night_Owl

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Re: Utrogestan
« Reply #17 on: December 03, 2011, 11:01:05 AM »

Not wishing to be scaremongering here, however feel I have to relay this ...

I've had it drummed into me at the meno clinic that low dose prog - ie. 100 mg Utrogestan x 7 or 10 days per month is NOT sufficient protection - also they no longer recommend the quarterly use.

Doc implied prescription of prog at the clinic is v.much experimental, trial and error for the individual - and I guess they are erring on the side of caution.

As others have mentioned on other threads, can only think the low dose would be acceptable along with yearly endo scan.

Night_Owl
x
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Night_Owl

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Re: Utrogestan
« Reply #18 on: December 03, 2011, 11:12:13 AM »

Hurdity, think you have posted similar info.

Meno doc explained, from their recent stats, for monthly (sequi) use prog:

(forgot to ask over what period of time though, dang! Sorry - that's such a relevant point!!!!)

Utro 200 mg x 12 per month = 1%  chance of hyperplasia
                   x 10                 = 2%
                   x 7                   = 4%
 
Same for Cyclogest 400 mg
 
NB: Utro 200 mg NOT 100
      Cyclo 400 mg NOT 200

Recommended: back to Cyclo 400 x 10 per month, try rectal use, as though I don't tolerate it all well, it's slightly better than Utro, a bit less sedative.

Night_Owl

 
« Last Edit: December 03, 2011, 11:14:30 AM by Night_Owl »
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bombus

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Re: Utrogestan
« Reply #19 on: December 03, 2011, 11:19:58 AM »

Hi Ladies,

I'm on 7 days of utrogestan 100mg oral route starting the 1st of each month. John Studd told me to expect a withdrawal bleed on day 10 but as it is a low dose gestogen it does not always produce a bleed. I just hope I don't end up in bed with a hideous migraine when I finish the 7 days as that's what usually happened on the other regimes I've been on.

My GP thinks I might have to have regular scans with the P being so low but that's fine with me.

I'm on day 3 of the 7 days at the moment and the only thing I've noticed is I'm sleeping really well.

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oldsheep

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Re: Utrogestan
« Reply #20 on: December 03, 2011, 05:42:13 PM »

I'm on oestradiol valerate 1mg tabs with 100 mg Utrogestan x 12-13 days p.m.  I haven't had a bleed for months now so may have to up the Utrogestan to 200mgs.

Gynae said at the outset that it could be the low oestrogen level that means I am not bleeding, but I think I am to have a scan in January to check.
I know he does not like the continuous progesterone idea but prefers 10 days - 2 weeks p.m.
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Taz2

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Re: Utrogestan
« Reply #21 on: December 04, 2011, 10:27:57 AM »

Hi Bombus I see you say "My GP thinks I might have to have regular scans with the P being so low but that's fine with me."

Will these scans be available on the NHS or will you have to pay for them?

Taz x
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Rivadan

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Re: Utrogestan
« Reply #22 on: December 04, 2011, 11:01:18 AM »

Gordon Bennett .... inconsistencies or what??? Wouldn't it be great if all the medics were singing from the same hymn sheet on this.

I'm hoping the foggyheaded feeling will ease off as the days go by. Yesterday was horrible. I felt so lethargic all day long. Also noticed I had a very dry mouth too. Can't see me going through this every month. Was optimistic about the quarterly regime - but then there seems to be a question mark over that too! Grrrrrr...........
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Hurdity

  • Guest
Re: Utrogestan
« Reply #23 on: December 04, 2011, 12:08:53 PM »

oldsheep - yes that is probably the case ie the oestrogen just isn't  enough to build up anything - not sure how far into meno you are? After 4 years of sequi my bleeds stopped. I then stopped HRT and had a scan and the lining was thin. I was on patches but the same dose usual for post meno (50 mcg).

Good that they have suggested a scan though to be on the safe side!

I would hope that if a GP suggests annual scans as a result of their prescribed treatment (eg low dose prog because you are so intolerant) that they would be on the NHS!! It is only a luxury if you decide yourself!

Nightowl yes those stats ring a bell - unless they've been updated Studd refers to them in his 1997 prog inolerance paper that Candy put up ( I can post the link if anyone wants it). He refers to earlier research from 1978 and 1980 - but the figures he quotes are: 0% hyperplasia with 12 days prog per month, 2% with 10 days and 4% with 7 days.

I presume they will have been updated so may be less favourable as you say 1 % chance with 12 per month - surely this mean we are all at risk who are on cyclical? I would imagine the research would have been done over 9 months to a year minimum ( the 1978 work was 9 months).

And I suppose the fact they are inconsistent is that the specialists like Studd,  and Panay and his clinic ( the latter which I understand can be available on the NHS), are actually doing and publishing the research, but some of the GPs for example will not have read up on all of this and will only go on the licensed products.

It's great to share all this knowledge and experiences - at least we can see the range of responses we all have which is sometimes so different but can be the same - eg tiredness on Utro.....

Hurdity x  :)
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bombus

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Re: Utrogestan
« Reply #24 on: December 04, 2011, 08:48:15 PM »

Hi Taz,

The scans will be on the NHS. How did you get on with the Utrogestan?
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Taz2

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Re: Utrogestan
« Reply #25 on: December 04, 2011, 09:00:36 PM »

I haven't started it yet due to this and that. I have lots of different things coming up that I had to go to and also was on antibiotics when the right day came round to start them. I was already feeling not so great so thought I would put it off for another month. Although I had started the Evorel 50 I also had two progesterone containing patches left of the Femseven so I used those.  Naughty I know.

Taz  :D
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bombus

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Re: Utrogestan
« Reply #26 on: December 05, 2011, 08:11:16 AM »

I've been naughty quite a few times as far as the P part of HRT is concerned. Hope you have a positive experience with the Utrogestan.

Bx
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Rivadan

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Re: Utrogestan
« Reply #27 on: December 05, 2011, 09:58:27 AM »

Considering my GP felt I should be "absolutely fine" taking oestrogen only for 3 months, I think there's a little 'wriggle room' we can take advantage of. I've always missed the P part once a year for my hols.
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silverlady

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Re: Utrogestan
« Reply #28 on: December 05, 2011, 04:32:08 PM »

Here is some info about Utrogestin that might be of interest.

http://jcem.endojournals.org/content/73/2/373.abstract

silverlady x
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Hurdity

  • Guest
Re: Utrogestan
« Reply #29 on: December 05, 2011, 05:14:22 PM »

Thanks for that link silverlady!
I can't pretend that I understand lipoprotein and cholesterol metabolism but the most interesting part was the last sentence "These results suggest that Utrogestan has lower potency of androgenic action and has desirable effects when given in cyclic combination with estrogen. "
I can see also that for those with hysterectomy this would also be interesting, and I believe, also demonstrates one aspect of the metabolic role of natural progesterone, given in prescribed doses.
Hurdity x  :)
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